Paula Ruiz-Rodriguez

Bioinformatician at PathoGenOmics Lab

I2SysBio

Biography

I study the genes of the deadless pathogens in the world: SARS-CoV-2 and Mycobacterium tuberculosis. I am interested in the understanding of these pathogens with a bioinformatics aproach, with a focus on open-source methods.

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Interests

Bacterial Evolution
Genetics and pathogenesis of Mycobacterium tuberculosis
Epidemiology of SARS-CoV-2
Phylogenetics and Phylogenomics
Scientific Illustration

Education

PhD in Biodiversity and Evolutionary Biology, 2024

University of Valencia
MSc in Bioinformatics, 2021

University of Valencia
BSc in Biology, 2019

University of Valencia

Skills

R programming

Python programming

Bash programming

Statistics

Photoshop

3d modelling

Experience

Research technician

CSIC-Institute for Integrative Systems Biology

Jul 2021 – Present Valencia

Bioinformatician at PathoGenOmics lab

Research technician

University of Valencia-Institute for Integrative Systems Biology

Nov 2020 – Jun 2021 Valencia

Bioinformatician at PathoGenOmics lab

Featured Publications

Paula Ruiz-Rodriguez, Clara Francés-Gómez, Álvaro Chiner-Oms, Mariana G. López, Santiago Jiménez-Serrano, Irving Cancino-Muñoz, Paula Ruiz-Hueso, Manuela Torres-Puente, María Alma Bracho, Giuseppe D’Auria, Llúcia Martinez-Priego, Manuel Guerreiro, Marta Montero-Alonso, María Dolores Gómez, José Luis Piñana, SeqCOVID-SPAIN Consortium, Fernando González-Candelas, Iñaki Comas, Alberto Marina, Ron Geller, and Mireia Coscolla

November 2021 In mBio

Evolutionary and Phenotypic Characterization of Two Spike Mutations in European Lineage 20E of SARS-CoV-2

We have detected two mutations in the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at amino acid positions 1163 and 1167 that appeared independently in multiple transmission clusters and different genetic backgrounds.They generate a whole new cluster inside 20E.

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Recent Publications

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Paula Ruiz-Rodriguez, Clara Francés-Gómez, Álvaro Chiner-Oms, Mariana G. López, Santiago Jiménez-Serrano, Irving Cancino-Muñoz, Paula Ruiz-Hueso, Manuela Torres-Puente, María Alma Bracho, Giuseppe D’Auria, Llúcia Martinez-Priego, Manuel Guerreiro, Marta Montero-Alonso, María Dolores Gómez, José Luis Piñana, SeqCOVID-SPAIN Consortium, Fernando González-Candelas, Iñaki Comas, Alberto Marina, Ron Geller, and Mireia Coscolla (2021). Evolutionary and Phenotypic Characterization of Two Spike Mutations in European Lineage 20E of SARS-CoV-2. In mBio.

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Marta Dafne Cabañero-Navalon, Víctor García-Bustos, Paula Ruiz-Rodriguez, Iñaki Comas, Mireia Coscollá, Llúcia Martinez-Priego, José Todolí, Pedro Moral Moral (2021). Persistent SARS-CoV-2 infection with repeated clinical recurrence in a patient with common variable immunodeficiency. In Clinical Microbiology and Infection.

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